换一批摘要土贝母苷甲为葫芦科植物土贝母中含量较大，水溶性、稳定性较好的三萜皂苷类活性成分，对肺癌、结直肠癌、乳腺癌、胃癌等多种肿瘤具有广泛的抑制作用。其机制主要与抑制肿瘤细胞生长、诱导肿瘤细胞凋亡、抑制肿瘤细胞侵袭转移、诱导细胞自噬、抑制肿瘤血管生成等途径相关。
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abstractsTubeimoside-1 (TBMS1) is a triterpene saponins active components with large content in Cucurbitaceae plant Fritillaria, which is water-soluble and stable. It has a broad inhibitory effect on lung cancer, colorectal cancer, breast cancer, gastric cancer and other tumors. The mechanism is mainly related to the inhibition of tumor cell growth, induction of tumor cell apoptosis, inhibition of tumor cell invasion and metastasis, induction of cell autophagy, and inhibition of tumor angiogenesis.
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关键词
土贝母土贝母皂苷甲肿瘤抗肿瘤药，植物（中药）作用机制综述Bolbostemmatis RhizomaTubeimoside-1TumorAntineoplastic drugs, phytogenicMechanism of actionReview
栏目名称
DOI
10.3760/cma.j.cn115398-20200913-00123
发布时间
2022-01-30（万方平台首次上网日期，不代表论文的发表时间）
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