摘要目的 对英文版下肢静脉溃疡患者生命质量问卷(VLU-QoL)进行汉化,评价汉化后的中文版VLU-QoL的测量性能,探索其在国内下肢静脉溃疡(VLU)患者中的适用性.方法 征得原作者和版权作者的同意后,采用国际药物经济学会制定的翻译标准对英文版VLU-QoL进行汉化,将中文版VLU-QoL应用于182例VLU患者,并对施测结果进行项目分析和信效度检验.结果 中文版VLU-QoL共有34个条目,总的Cronbach a系数为0.940;评定者间信度为0.841;重测信度为0.825;问卷条目水平的内容效度指数的范围为0.83～1.00,量表水平的内容效度指数为0.955;因子分析共提取3个公因子,累积方差贡献率为54.367％;中文版VLU-QoL与简明健康测量量表生理健康、心理健康的相关系数即校标关联效度分别为0.714和0.541.结论 中文版VLU-QoL具有良好的信效度,可以用于评价VLU患者的生命质量.

abstractsObjective To translate the Venous Leg Ulcer Quality of life Questionnaire (VLU-QoL) into Chinese and evaluate the reliability and validity of Chinese version.Methods VLU-QoL was translated into Chinese according to the standards setted by ISPOR.Totally 232 patients with venous leg ulcer were recruited and investigated by the Chinese version of VLU-QoL.Results The Chinese version of VLU-QoL comprised 34 items,Cronbach α was 0.940,inter-rater reliability was 0.841;test-retest reliability was 0.825.I-CVI was 0.83-1.00,S-CVI/Ave was 0.955;Criterion-related validity were 0.714 and 0.541;factor analysis got 3 factors,which explained 54.367％ of the total variance.Conclusions The Chinese version of VLU-QoL has been proved to be reliable and valid.It can be used as a valid tool for the measurement of quality of life for patients with venous leg ulcer.