摘要目的:系统评价癌症患者经济毒性的发生率、影响因素及应对策略。方法:系统检索PubMed、Embase、the Cochrane Library、Web of Science、CINAHL、中国生物医学文献数据库、中国知网、万方数据库和维普数据库关于癌症患者经济毒性的相关文献，检索时限为建库至2022年6月。采用Stata 14.0软件对癌症患者经济毒性及应对策略发生率进行单组Meta分析。对影响因素采取描述性分析。结果:共纳入25篇文献，包括2 939例癌症患者。Meta分析结果显示，癌症患者经济毒性的发生率为47%（95% CI 39%~55%）。经济毒性的影响因素包括社会人口学因素、疾病相关因素、医保相关因素以及心理因素。应对策略包括物质应对和医疗应对。 结论:癌症患者经济毒性发生率高，与多种因素相关，医护人员应重视癌症患者的早期筛查，动态收集患者支出项目等相关数据，持续评估患者的经济状况，做好相关预防工作。

abstractsObjective:To systematically review the prevalence, influencing factors of financial toxicity and coping strategies in cancer patients.Methods:The studies on financial toxicity among cancer patients were searched in PubMed, Embase, The Cochrane Library, Web of Science, CINAHL, WangFang Data, CNKI, Sinomed, VIP from inception to June 2022. Stata14.0 software was used to analyze the prevalence of financial toxicity and coping strategies with a single group meta-analysis. Descriptive analysis was used to analyze the influencing factors.Results:A total of 25 papers including 2 939 cancer patients were included. Meta-analysis results showed that the prevalence of financial toxicity in cancer patients was 47% (95% CI 39%-55%). The influencing factors of financial toxicity included sociodemographic factors, disease related factors, medical insurance related factors and psychological factors. Conclusions:The high incidence of financial toxicity in cancer patients is associated with a variety of factors. Health care professionals should pay attention to early screening of cancer patients, dynamically collect relevant data such as patient expenditure items, continuously assess patients' economic status, and make relevant preventive efforts.