摘要目的:对国内外癌症患者症状群前哨症状的研究现状及存在问题进行综述，以供未来该领域研究参考。方法:计算机检索中国知网、万方数据、维普网、中国生物医学文献数据库、PubMed、Web of Science、Cochrane Library、Embase等数据库，收集自建库至2023年11月8日公开发表的关于癌症症状群前哨症状的相关文献，并进行描述性统计分析。结果:最终纳入16篇文献，发文量总体呈上升趋势，其中10篇为中文文献、6篇为英文文献。癌症患者症状群前哨症状热点主要包括：（1）纳入分析的症状群内症状数目为3～13个，症状群为1～8个，每篇文献探索到的症状群前哨症状数量为1～8个；（2）症状群前哨症状识别及动态变化；（3）症状群各前哨症状在不同癌症患者症状群中的差异；（4）基于不同统计方法进行特定症状群前哨症状分析；（5）基于症状群前哨症状的干预。结论:近几年癌症患者症状群前哨症状受到国内外学者关注，但存在发展不平衡、研究方法不统一等问题。需开展高质量识别研究，使纳入人群更具体、方法更科学统一，并关注症状群前哨症状对患者结局的影响和发生机制，以调查潜在机制并促进有效症状管理。将前哨症状作为干预切入点，降低症状群发生率，减轻患者症状困扰。

abstractsObjective:To review the current research and existing problems of symptom cluster sentinel symptoms in cancer patients both domestically and internationally, so as to provide reference for future research.Methods:The literature on sentinel symptoms of cancer symptom clusters, from the establishment of the database until November 8, 2023, was electronically searched on platforms such as China National Knowledge Infrastructure, WanFang Data, VIP, China Biomedical Database, PubMed, Web of Science, Cochrane Library, Embase and so on. Descriptive statistical analysis was conducted.Results:Sixteen articles were included, with an overall upward trend in publication volume, including 10 Chinese articles and 6 English articles. The sentinel symptom hotspots of cancer patients' symptom clusters mainly included: (1) the number of symptoms included in the analyzed symptom clusters was 3 to 13, the number of symptom clusters was 1 to 8, and the number of sentinel symptoms explored in each literature was 1 to 8; (2) Identification and dynamic changes of sentinel symptoms in symptom clusters; (3) Differences in sentinel symptoms among different symptom groups of cancer patients; (4) Analyzing specific sentinel symptoms of symptom groups based on different statistical methods; (5) Intervention based on sentinel symptoms of symptom clusters.Conclusions:In recent years, the symptom cluster sentinel symptoms of cancer patients have received attention from researchers at home and abroad, but there are problems such as uneven development and inconsistent research methods. High quality identification research is needed to make the included population specific and the methods scientifically unified, and to focus on the impact and mechanism of symptom cluster sentinel symptoms on patient outcomes in symptom clusters, so as to investigate potential mechanisms and promote effective symptom management.