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呼吸门控辅助下放射治疗肺癌的早期疗效

Short-term efficacy of respiratory gating-aided radiotherapy on lung cancer

摘要目的:分析呼吸门控技术辅助下放射治疗肺癌的早期疗效。方法研究组48例经病理组织学和(或)细胞学确诊的非小细胞肺癌患者接受呼吸门控技术辅助下的放射治疗,另选取基础条件相似的48例非小细胞肺癌患者作为对照组接受传统方式的放疗,放疗的剂量与周期相同,比较两组的近期总有效率和并发症情况。结果随访时间为6个月,研究组和对照组总有效率分别为91.7%和85.4%,研究组的总有效率高于对照组,两组比较差异具有统计学意义,α<0.05;研究组和对照组的放射性肺炎发生率分别为10.4%和16.7%,研究组的急性毒副反应显著小于对照组,α<0.05。结论呼吸门控技术辅助下放射治疗肺癌安全、有效,近期疗效满意,远期疗效需要进一步观察。

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abstractsObjective To investigate the short ? term efficacy of respiratory gating ? aided radiotherapy on lung cancer. Methods Forty?eight patients with non?small cell lung cancer (NSCLS) diagnosed by pathologic histology and/or cytology(study group)were treated with respiratory gating?aided radiotherapy. Another 48 NSCLC patients with the similar baseline characteristics (control group) were treated with conventional radiotherapy. With the same dosage and duration of radiotherapy,the short?term total effective rate and complication between the two groups were compared. Results The length of follow?up was 6 months. The total effective rate in the study group was 91.7%,which was higher than 85.4%in the control group,with a statistical difference between the two groups (α<0.05). The incidence of radiation pneumonia in the study group was 10.4%,which was significantly lower than 16.7% in the control group, and there was a statistical difference between the two groups(α<0.05). Conclusion Radiotherapy on lung cancer under respiratory gating is safe and effective,with satisfactory short?term efficacy. However,the long?term efficacy remains to be investigated in further observation.

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DOI 10.3760/cma.j.issn.1674-1927.2015.01.017
发布时间 2015-08-28(万方平台首次上网日期,不代表论文的发表时间)
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