摘要结直肠癌腹膜转移传统上被认为是肿瘤终末期表现之一.近年来,细胞减灭术联合腹腔热灌注化疗在延长患者生存时间和延缓肿瘤复发等方面取得较大进展.国内外结直肠癌治疗指南将细胞减灭术联合腹腔热灌注化疗作为腹膜转移的有效治疗方式.本文对其治疗方式进行概述,并结合结直肠癌腹膜转移治疗领域研究进展和笔者临床经验,展望未来发展方向.

abstractsColorectal cancer peritoneal metastasis has traditionally been considered as one of the end-stage manifestations.Recently,cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy achieved promising results in prolonging survival of patients and reducing tumor recurrences.Many guidelines suggested that the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is an acceptable treatment for peritoneal metastasis.This article highlighted the treatment method,reviewed the latest evidence in treatment of colorectal cancer peritoneal metastasis and explored future direction.