摘要目的:系统评价高度近视白内障患者行超声乳化白内障吸除及人工晶状体(IOL)联合囊袋张力环(CTR)植入术的治疗效果。方法:计算机检索外文数据库MEDLINE、EMBASE、Cochrane Library以及中文数据库中国知网、万方数据、维普数据库自建库起至2020年10月的同行评议文献，收集有关高度近视白内障患者行超声乳化白内障吸除及IOL联合CTR植入术(试验组)与白内障超声乳化吸除及IOL植入术(对照组)相比较的临床研究。根据纳入标准和排除标准进行文献筛选、资料提取和质量评价。应用RevMan 5.3软件，以平均差( MD)、比值比( OR)分别衡量计量资料和计数资料的效应量，对术后最小分辨角对数最佳矫正视力(BCVA)、后发性白内障(PCO)、囊袋收缩综合征(CCS)、视网膜脱离(RD)等进行meta分析。 结果:本研究共纳入8篇文献，共2 085眼，其中试验组1 054眼，对照组1 031眼。meta分析结果显示，试验组与对照组患者术后1周、1个月、3个月BCVA比较差异均无统计学意义(均 P>0.05)，术后6个月试验组患者BCVA高于对照组，差异有统计学意义( MD：－0.11；95% CI：－0.15~－0.07； P<0.01)。试验组患者术后PCO发生率低于对照组，差异有统计学意义( OR：0.24；95% CI：0.15~0.36； P<0.01)。试验组患者术后CCS发生率低于对照组，差异有统计学意义( OR：0.08；95% CI：0.01~0.65； P＝0.02)。试验组患者术后RD发生率低于对照组，差异有统计学意义( OR：0.21；95% CI：0.05~0.82； P＝0.02)。 结论:联合应用CTR治疗高度近视白内障能提高术后视觉质量，减少术后PCO、CCS和RD的发生。

abstractsObjective:To systematically evaluate the efficacy of phacoemulsification and intraocular lens (IOL) with and without capsular tension ring (CTR) in patients with high myopia and cataract.Methods:MEDLINE, EMBASE, Cochrane Library, and Chinese databases including CNKI, Wanfang Data, and VIP databases were searched from their establishment to October 2020 to obtain peer-reviewed clinical studies comparing the efficacy of cataract phacoemulsification and IOL implantation combined with CTR implantation (experimental group) and cataract phacoemulsification and IOL implantation (control group) in patients with high myopia and cataract.Literature screening, data extraction and methodological quality assessment were implemented based on inclusion and exclusion criteria.A meta-analysis of postoperative best corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution unit, posterior capsular opacification (PCO), capsular contraction syndrome (CCS), retinal detachment (RD) was performed using Revman 5.3 software with mean difference ( MD) and odds ratio ( OR) describing the effect sizes of measurement data and count data, respectively. Results:Eight studies with 2 085 eyes were included in this study, including 1 054 eyes in the experimental group and 1 031 eyes in the control group.Meta-analysis showed that there was no significant difference in BCVA between the two groups at 1 week, 1 month, and 3 months after surgery, but the improvement in BCVA at 6 months after surgery was significantly better in the experimental group than in the control group ( MD: -0.11; 95% CI: -0.15--0.07; P<0.01). The incidence rates of postoperative PCO ( OR: 0.24; 95% CI: 0.15-0.36; P<0.01) and CCS ( OR: 0.08; 95 % CI: 0.01-0.65; P=0.02) and RD ( OR: 0.21; 95% CI: 0.05-0.82; P=0.02) were lower in the experimental group than in the control group, and the differences were statistically significant. Conclusions:The combination of CTR in the treatment of patients with high myopia and cataract can improve the postoperative visual quality and reduce the incidence of postoperative PCO, CCS and RD.