摘要目的:比较Pentacam、VX1202种设备测量中央角膜厚度(CCT)、最薄点角膜厚度(MinCT)和前房深度(ACD)的一致性.方法:系列病例研究.2018年3-4月在北京同仁医院就诊拟行屈光手术的近视患者71例(142眼),分别使用Pentacam和VX120测量CCT、MinCT和ACD.采用Rosner-Glynn-Lee法对双眼资料进行校正,采用配对秩和检验对不同设备测量值进行组间比较;采用组内相关系数和Bland-Altman 95％一致性界限法衡量不同设备测量值的一致性.结果:与Pentacam相比,VX120测量的CCT和ACD较小(Z=3.524、7.446,均P<0.001),VX120和Pentacam测量的MinCT差异无统计学意义(Z=0.679,P=0.497).VX120与Pentacam测量的MinCT的组内相关系数达到0.9,且Bland-Altman图提示93.7％的数据分布在可信区间内.两者测量的MinCT的95％一致性区间是-27.81～29.26μm.结论:VX120与Pentacam测量的MinCT具有很高的一致性.但在临床工作中,还应考虑其他指标的差异,不可直接替代.

abstractsObjective: To compare the consistency of central corneal thickness (CCT), minimum corneal thickness (MinCT) and anterior chamber depth (ACD) measured by Pentacam and VX120. Methods: In this case series study, 71 myopia patients with (142 eyes) who planned to receive refractive surgery were enrolled from the March 2018 to April 2018, in Beijing Tongren Hospital. All subjects were under CCT, MinCT, ACD measurement by Pentacam and VX120. Due to that data of both eyes were used, thus a Rosner-Glynn-Lee method was used to make correction. The clustered rank sign test was used to compare the measurements of different equipment. The intra-class correlation coefficient (ICC) and Bland-Altman 95％limits of agreement were used to measure the consistency of measurement of different equipment. Results:CCT, ACD measured by the VX120 was lower than Pentacam (Z=3.524, 7.446, all P<0.001). There was&nbsp;no statistical difference in the measurement of MinCT between VX120 and Pentacam (Z=0.679, P=0.497). The ICC of MinCT measured by VX120 and Pentacam was 0.9 and the Bland-Altman plot showed that 93.7％ of the data were distributed within the confidence interval. The 95％ limits of agreement of MinCT were -27.81 to 29.26 μm for these two devices. Conclusions: VX120 has a high consistency with Pentacam on the measurement of MinCT. However, the measurements acquired by VX120 should not be directly interchangeable with Pentacam measurements in clinical practice.