摘要1例65岁男性患者因2型糖尿病、糖尿病肾病及慢性肾功能不全给予红豆杉饮片(10 g,1次/d口服)、门冬胰岛素30(10 U,3次/d皮下注射)、甘精胰岛素(10 U,每晚皮下注射)、胰激肽原酶(40 U,1次/d口服)、硫辛酸(0.6g、1次/d静脉滴注)、海昆肾喜胶囊(0.44g,3次/d口服)、尿毒清颗粒(5 g,3次/d口服)及复方α-酮酸(4片,3次/d口服)等治疗.患者第2次口服红豆杉饮片后约1h出现恶心呕吐;约4h突发四肢抽搐,心电监护示室性心动过速,实验室检查示血钾6.4 mmol/L.室性心动过速反复发作,给予电复律5次,并给予利多卡因、胺碘酮等药物治疗后,转为窦性心律.停用红豆杉饮片,其余药物继续应用,患者未再发生室性心动过速.

abstractsA 65-year-old male patient with diabetes, diabetic nephropathy, and chronic renal insufficiency received treatments of Taxus chinensis medicinal slices (10 g, once daily by mouth).insulin aspart 30 (10 U, thrice daily by subcutaneous injection), insulin glargine (10 U, once every night by subcutaneous injection), pancreatic kininogenase (40 U, once daily by mouth), thioctic acid (0.6 g, once daily by Ⅳ injection), Haikunshenxi capsules(海昆肾喜胶囊,0.44 g,thrice daily by mouth), Niaoduqing granules(尿毒清颗粒,5 g,thrice daily by mouth), and compound α-keto acid (4 pills,thrice daily by mouth).The patient developed nausea and vomiting and convulsion of extremities after 1 h and 4 h of the second treatment of Taxus chinensis medicinal slices.ECG monitoring showed supraventricular tachycardia.Laboratory tests showed serum potassium 6.4 mmol/L.Recurrent supraventricular tachycardia appeared in the patient.After 5 times of electrical cardioversion and lidocaine and amiodarone treatments,the patient's arrhythmia was converted to sinus rhythm.Taxus chinensis medicinal slices was stopped and other treatments were continued.Supraventricular tachycardia did not recur.