摘要1例58岁男性患者因急性缺血性脑卒中给予阿司匹林肠溶片200 mg口服、1次/d,瑞舒伐他汀钙片10 mg口服、1次/d,丁苯酞氯化钠注射液100 ml(含丁苯酞25 mg,氯化钠0.9 g)静脉滴注、2次/d,曲克芦丁脑蛋白水解物10 ml静脉滴注、1次/d.7 d后实验室检查示血尿素6.9 mmol/L, Scr 131 μmol/L,血胱抑素C 1.54 mg/L,考虑可能为丁苯酞氯化钠注射液所致肾损伤.停用该药,继续应用其他药物,并给予注射用血栓通和百令胶囊等药物治疗.6 d后复查,血尿素6.2 mmol/L,Scr 104 μmol/L,血胱抑素 C 1.05 mg/L;2个月后复查,血尿素5.9 mmol/L,Scr 101 μmol/L,血胱抑素C 1.00 mg/L.

abstractsA 58-year-old male patient received aspirin enteric-coated tablets 200 mg and rosuvastatin calcium 10 mg once daily by mouth,IV infusions of butylphthalide and sodium chloride injection 100 ml (containing butylphthalide 25 mg and sodium chloride 0.9 g)twice daily and troxorutin brain protein hydrolysate 10 ml once daily for acute ischemic stroke. Seven days later,laboratory tests showed blood urea 6.9 mmol/L,serum creatinine (Scr)131 μmol/L,and blood cystatin C 1.54 mg/L. Kidney injury induced by butylphthalide and sodium chloride injection was considered. Butylphthalide and sodium chloride injection was stopped but the other drugs as well as Xueshuantong for injection (注射用血栓通)and Corbrin capsule (百令胶囊)were given. Laboratory tests showed blood urea 6.2 mmol/L,Scr 104 μmol/L,and blood cystatin C 1.05 mg/L 6 days later and then blood urea 5.9 mmol/L,Scr 101 μmol/L,and blood cystatin C 1.00 mg 2 months later.