摘要Objective To evaluate the effect and mechanism of largehead atractylodes rhizome on the serum albumin level and jejunal mucosa morphology in rats with cerebral hemorrhage. Methods The cerebral hemorrhage rat model was established by using a simple grouping experimental design method to detect the serum albumin level and the morphological parameter of the jejunal mucosa in the treatment and control groups on Day 1, 7 and 14 after cerebral hemorrhage. Results Compared with the control group, the serum albumin was increased in the treatment group on Day 1 and 7 after the operation (P<0.05), the small intestinal villus height and mucosal thickness were significantly decreased on Day 1, and the small intestinal villus height, villus area and mucosal thickness were all significantly increased (P<0.01). Conclusion Largehead atractylodes rhizome can increase the serum albumin level of rats, and can aggravate the injury of the small intestinal mucosa in the early stage, but relieve in the late stage.