摘要目的 了解北京市延庆县肾综合征出血热(HFRS)流行特征和鼠间带毒情况,为采取有效控制措施、降低发病率提供依据.方法 对2005-2007年HFRS病例资料和鼠间抗原检测资料进行回顾分析,分析指标包括发病率、鼠间抗原及抗体阳性率.结果 2005-2007年每年均有发病,发病率为2.36/10万(7/296 031)、132/10万(4/304 941)、0.94/10万(3/318 418),1-6月份为发病高峰;病例发病年龄集中于15～21岁,占7/14;职业以农民为主,占5/14;男性多于女性(6:1).延庆县鼠间抗原阳性率为2.22%(5/225),优势鼠种为社鼠,抗原阳性率为3.12%(4/128).结论 延庆县HFRS发病率呈下降趋势,鼠间带毒率较高,应采取综合措施,进一步加强对HFRS的预防控制.

abstractsObjective To understand the epidemic characters and morbidity tendency of hemorrhagic fever with renal syndrome(HFRS) and the situation of rats with HFRS virus in Yanqing County, to get solid scientific basis for controlling the disease and to prevent the spread of epidemics. Methods Surveillance data on HFRS from 2005 to 2007 were analyzed retrospectively and the indictors included incidence and the positive ratios of the antigen and antibody in rats. Results Every year had HFRS cases from 2005 to 2007, and the incidence was 2.36,1.32,0.94 per one hundred thousand, respectively. Cases in the group aged 15-21 accounted for 7/14. Most cases were farmers,accounting for 5/14. Male cases were more than female cases with the ratio of 6 : 1. The positive ratio of 2.22%(7/14) was found in titer test of HFRS antigen. The predominant mice were Niviventer confucianus, and the positive ratio of HFRS antigen was 3.12% (4/128) in Niviventer confucianus. Conclusions The HFRS incidence in Yanqing County has been decreasing year by year, but the infection rate of HFRS is rather high. Comprehensive control measures should be taken to strengthen prevention and control of HFRS.