摘要目的 了解行政区域变动对杭州市饮水型地方性氟中毒(地氟病)防治现状的影响,为评价和完善防治策略提供科学依据.方法 2017年调查杭州市所有历史性饮水型地氟病病区村行政区域现状,以及改水工程运行情况.检测现病区自然村水氟含量,8～ 12岁儿童氟斑牙及尿氟含量.水氟含量检测采用《生活饮用水标准检验方法》(GB/T 5750.7-2006),氟斑牙检查采用Dean法,尿氟含量检测采用离子选择电极法.结果 杭州市历史饮水型地氟病病区现涉及5个县(市、区)、8个乡镇、22个行政村的38个自然村,全部病区自然村已完成改水且改水工程运转正常,水氟含量均＜ 1.00 mg/L;共检查795名8～ 12岁儿童,氟斑牙检出率为1.13％(9/795).共检测尿样198份,尿氟几何均数为0.77 mg/L,范围为0.12～2.90 mg/L.结论 行政区域的变动并未影响改水降氟效果,但仍应加强改水工程的后期管理维护和病情监测工作.

abstractsObjective To investigate the effects of administrative region changes on prevention and control of fluorosis,in order to provide a scientific basis for evaluation and improvement of prevention and control measures.Methods An investigation was conducted in all drinking water-born endemic fluorosis areas in Hangzhou in 2017,to evaluate the status quo of water-improving defluoridation projects,measure the water fluoride content with "the Standard Detection Methods for Domestic Drinking Water" (GB/T 5750.7-2006),detect the dental fluorosis with Dean method and the urinary fluoride content by fluoride selective electrode method in children aged 8 to 12 years old.Results The historical endemic fluorosis areas in Hangzhou now involved 38 natural villages of 22 administrativevillages in 8 townships of 5 counties (cities and districts).All villages had completed water-improving projects which were running well as the fluoride contents of drinking water were less than 1.00 mg/L.The detection rate of dental fluorosis was 1.13％ (9/795) among children aged 8-12 years.A total of 198 urine samples were tested,the urinary fluoride content varied from 0.12 to 2.90 mg/L,and the geometric mean was 0.77 mg/L.Conclusion Administrative region changes do not influence the effect of water-improving defluoridation projects,but management and monitoring of the water-improving projects still should be strengthened.