摘要目的 了解河北省黄骅市体检人群桥本甲状腺炎(HT)的检出情况以及合并甲状腺功能异常的发生情况.方法 采用资料回顾性分析方法,收集2014-2016年在河北省沧州中西医结合医院体检的黄骅市居民甲状腺检查资料,并对HT患者检出情况以及合并甲状腺功能异常的情况进行分析.结果 共收集4 413名体检者检查资料,年龄为(45.76±10.13)岁;其中男性2 099例、女性2 314例.黄骅市体检人群的HT检出率为6.55％(289/4413),且有逐年增高的趋势(x2趋势=7.126,P＜0.05).不同性别间HT检出率(男性:2.86％,女性:9.90％)比较差异有统计学意义(x2=89.077,P＜0.05);不同年龄组间女性HT检出率比较差异有统计学意义(x2=18.541,P＜0.05),男性HT检出率比较差异无统计学意义(x2=8.424,P＞0.05).HT患者合并甲状腺功能异常的检出率为25.61％ (74/289),其中40～＜50岁组检出率最高,为34.74％(33/95);合并甲状腺功能亢进(甲亢)、甲状腺功能减退(甲减)和亚临床甲状腺功能减退(亚甲减)的检出率分别为3.11％(9/289)、6.57％(19/289)、15.92％(46/289),HT合并亚甲减患者的检出率较高.结论 黄骅市人群的FHT检出率逐年升高,部分HT患者伴有甲状腺功能异常,其中合并亚甲减的检出率最高.应加强HT的早期诊断,及时采取相应的防治措施,减少HT伴甲状腺功能异常的发生.

abstractsObjective To understand the detection rate of hashimoto's thyroiditis (HT) and the occurrence of abnormal thyroid function in medical examination population in Huanghua City,Hebei Province.Methods Using the retrospective analysis method,the thyroid examination data of residents of Huanghua City who were examined in the Cangzhou Hospital of Traditional Chinese and Western Medicine in Hebei Province from 2014 to 2016 were collected,the detection rate of HT and the occurrence of abnormal thyroid function were analyzed.Results A total of 4 413 people were examined,aged (45.76 ± 10.13) years old;including 2 099 males and 2 314 females.The HT detection rate of the medical examination population in Huanghua City was 6.55％ (289/4 413),and there was a trend of increasing year by year (x2trend =7.126,P ＜ 0.05).The difference in HT detection rates between different genders (male:2.86％,famale:9.90％) was statistically significant (x2 =89.077,P ＜ 0.05);there was a statistically significant difference in the HT detection rates among women of different age groups (x2 =18.541,P ＜ 0.05),and there was no significant difference in the detection rates of HT among men of different age groups (x2 =8.424,P ＞ 0.05).The incidence of abnormal thyroid function in HT patients was 25.61％ (74/289),of which the highest detection rate was 34.74％ (33/95) in the 40-＜ 50 years old group;the detection rates of HT with hyperthyroidism,hypothyroidism and subclinical hypothyroidism were 3.11％ (9/289),6.57％ (19/289) and 15.92％ (46/289),respectively.The detection rate of HT with subclinical hypothyroidism was higher.Conclusions The HT detection rate of the population in Huanghua City has increased year by year,and some HT patients are associated with abnormal thyroid function,and their detection rate of HT with subclinical hypothyroidism is the highest.Early diagnosis of HT should be strengthened,and appropriate prevention and treatment measures should be taken in time to reduce the occurrence of HT with abnormal thyroid function.