摘要目的 分析2012-2017年山西省人间布鲁菌病(简称布病)监测结果,掌握山西省布病疫情现状,为制定布病防治对策、措施提供科学依据.方法 收集山西省2012-2017年布病疫情数据和监测数据,采用回顾性分析方法,分析布病“三间分布”特征、布病爆发疫情分布及4个布病监测点血清学和病原学监测结果.结果 2012-2017年,山西省共报告布病36 220例,平均发病率为16.62/10万,其中2014年报告新发布病8 540例,发病率为23.53/10万;报告病例主要集中大同市、朔州市、晋中市和忻州市,共报告布病23 197例,占全省报告病例总数的64.04％.布病发病呈季节性,流行高峰期为3-8月,占全省报告病例数的67.23％(24 350/36 220);发病以青壮年、男性、农牧民为主,分别为23 084、28 317、32 616例.监测点流行病学调查重点职业人群39 140例,血清学检查10 536例,阳性585例,阳性率为5.55％,各监测点血清学检查阳性率以天镇县最高,为9.50％(226/2 378).病原学血培养626份,分离到布鲁菌107株,总出菌率为17.09％,除1株羊种布鲁菌变异株外,其他均为羊种3型.结论 山西省布病疫情近几年有下降趋势,但布病疫情仍然较重,建议继续加强监测工作,及时掌握疫情动态,有效控制布病疫情.

abstractsObjective To analyze the epidemiological surveillance results of human brucellosis in Shanxi Province from 2012 to 2017,to know the epidemic status of brucellosis,and to provide evidence for prevention and control of brucellosis.Methods Incidence date and surveillance date of disease outbreaks in Shanxi Province from 2012 to 2017 were collected,the retrospective analysis method was used to analysis the "three distribution" of brucellosis,outbreak situation and the results of serological and pathogenic surveillance in the 4 surveillance stations.Results A total of 36 220 brucellosis cases were reported from 2012 to 2017,the average incidence was 16.62/100 000;8 540 brucellosis cases were reported in 2014,with incidence 23.53/100 000;a total of 23 197 cases of brucellosis were reported mainly in Datong,Shuozhou,Jinzhong and Xinzhou,accounting for 64.04％ of the province total.The onset was seasonal,and the peak of the epidemic was from March to August,accounting for 67.23％ (24 350/36 220).The brucellosis cases were mainly youth (23 084),male (28 317),farmers and herdsman (32 616).In the 4 surveillance stations of the brucellosis,39 140 cases were investigated,of which 10 536 cases did serological test,in which 585 were positive for Brucella (5.55％).The highest positive rate of serological test was 9.50％ (226/2 738) which was found in Tianzhen.A total of 626 samples carried out pathogen culture,in which 107 strains of brucellosis were detected,the detection rate was 17.09％,and 106 strains Brucella were melitensis biovar 3 of the total strains except 1 mutant.Conclusions The reported incidence in Shanxi Province is in a decline tendency,but the situation of brucellosis epidemic is still relatively serious.It is suggested that the surveillance work should be strengthened;the epidemic situation of brucellosis should be mastered in time and effectively controlled.