换一批
换一批摘要砷是一种广泛分布于自然环境的污染物,肝脏是砷毒性的主要靶器官之一,砷通过影响肝细胞凋亡的失衡从而造成肝脏损伤并引起肝脏疾病,然而其具体影响机制并不是十分明确.文中就近年来国内外砷导致肝细胞凋亡的通路和影响因素研究进行综述,为未来肝损伤机制的研究和临床防治提供一定参考.
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abstractsArsenic is a pollutant widely distributed in the natural environment.The liver is one of the main target organs of arsenic toxicity.Arsenic causes liver damage and liver disease by affecting the imbalance of hepatocyte apoptosis.However,its specific mechanism is not very clear.In this paper,the research on pathways and influencing factors of arsenic-induced hepatocyte apoptosis in recent years is reviewed,which might provide a reference for the mechanism study and clinical prevention of liver injury in the future.
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栏目名称
DOI
10.3760/cma.j.issn.2095-4255.2019.05.017
发布时间
2019-07-02
- 浏览169
- 被引10
- 下载100
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