摘要铁离子参与了某些胞内寄生菌的毒力和致病作用.在布鲁菌致病过程中,布鲁菌对宿主铁源的摄取、代谢与布鲁菌的胞内寄生、免疫逃逸密切相关.文中结合国内外文献资料,对布鲁菌铁离子摄取系统、铁离子应答调控因子、宿主对布鲁菌铁源的营养免疫进行阐述.
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abstractsIron is involved in the virulence and pathogenic effects of certain intracellular parasites.In the pathogenic process of Brucella,the uptaking and metabolism of host iron are closely related to intracellular parasitism and immunity escape of Brucella.In this paper,we elucidated the iron transport system,iron response regulators and nutrient immunity of iron based on the latest report and data about Brucella.
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