摘要目的:了解山东省水源性高碘地区重点人群碘营养水平，为适时采取针对性防治措施和科学调整干预策略提供依据。方法:2018年，以县（市、区，以下简称县）为单位开展监测工作，在划定的高碘地区以行政村为单位确定监测点。按照2017年山东省居民生活饮用水水碘调查结果，各监测县将水碘中位数> 100 μg/L的行政村按照水碘值进行排序，采取系统抽样方法，每个县抽取5个行政村，如果少于5个行政村则全部抽取（如果有水碘中位数> 300 μg/L的行政村，则至少保证抽取1个）。在所有监测点开展居民生活饮用水水碘含量，8 ~ 10岁儿童甲状腺容积、尿碘、盐碘，孕妇尿碘、盐碘的检测。采用《尿中碘的砷铈催化分光光度测定方法》（WS/T 107-2006）检测水碘和尿碘，B超法检测儿童甲状腺容积，半定量法检测盐碘。结果:共采集水样341份，水碘中位数为131.15 μg/L，范围为7.10 ~ 1 054.00 μg/L；共检测8 ~ 10岁儿童尿样7 555份，尿碘中位数为289.20 μg/L；8 ~ 10岁儿童甲状腺肿大率为3.10%（234/7 555）；检测孕妇尿样1 996份，尿碘中位数为179.90 μg/L；检测儿童、孕妇家中食用盐盐样9 551份，不加碘食盐率为86.25%（8 238/9 551）。结论:山东省水源性高碘地区孕妇尿碘处于适宜水平，儿童尿碘处于大于适宜量水平，因此仍需加大改水降碘的力度，并加强对重点人群的碘营养状况监测。

abstractsObjective:To investigate the iodine nutritional status of key population in waterbrone high iodine areas in Shandong Province and provide scientific basis for adjustment of control strategy.Methods:In 2018, the county (city, district, county for short) shall be the unit to carry out the monitoring work, and the administrative villages shall be the unit to determine the monitoring sites in the designated high-iodine areas. According to the results of the 2017 survey on drinking water iodine for residents of Shandong Province, each monitoring county sorted the administrative villages with a median water iodine above 100 μg/L according to the water iodine value and adopted a systematic sampling method. Each county took 5 administrative villages, and if there were less than 5 administrative villages, they were all extracted (if there were administrative villages with median water iodine above 300 μg/L, ensured at least one extraction). Among the monitoring sites, water iodine, children urinary iodine, salt iodine and thyroid volume, pregnant urinary iodine, and salt iodine were investigated. The "Arsenic Cerium Catalytic Spectrophotometry Method" (WS/T 107-2006) was used to detect the water iodine and urinary iodine contents; the B-ultrasound method was used to examine the thyroid volume of children; the semi-quantitative method was used to detect the salt iodine level of residents.Results:A total of 341 water samples were collected, the median water iodine was 131.15 μg/L, ranging from 7.10 to 1 054.00 μg/L. A total of 7 555 urine samples of children were tested and the median urinary iodine of children was 289.20 μg/L. The rate of goiter of children was 3.10% (234/7 555). A total of 1 996 urine samples of pregnant women were tested and the median urinary iodine of pregnant women was 179.90 μg/L. A total of 9 551 edible salt samples were collected from children and pregnant women, including 8 238 non-iodine salt samples and the consumption rate of non-iodine salt was 86.25% (8 238/9 551).Conclusions:The pregnant women are in a suitable state of iodine nutrition, the children's urinary iodine is at a higher than suitable level in waterbrone high iodine areas in Shandong Province. Therefore, it is still necessary to strengthen the efforts to improve water and reduce iodine, and strengthen the monitoring of iodine nutrition status of key populations.