摘要目的:掌握河北省非高碘地区8 ~ 10岁儿童和孕妇碘营养水平，为碘缺乏病防治研究工作提供科学依据和针对性的防治策略。方法:2018年对河北省162个县（市、区，以下简称县）进行碘营养分析，每个监测县按东、西、南、北、中划分5个抽样片区，每个片区抽取1个乡镇/街道，每个乡镇/街道抽取1所小学，每所小学抽取8 ~ 10岁非寄宿学生40人。每个监测县在所抽取的5个乡镇/街道中各抽取20名孕妇，儿童和孕妇均采集家中食用盐盐样和一次随机尿样检测盐碘和尿碘。盐碘含量检测采用《制盐工业通用试验方法碘的测定》（GB/T 13025.7-2012），川盐及其他强化食用盐采用仲裁法。尿碘含量检测采用《尿中碘的砷铈催化分光光度测定方法》（WS/T 107-2006）。结果:162个县共采集儿童家中食用盐盐样31 883份，其中碘盐28 539份，合格碘盐26 456份。人口标化后碘盐覆盖率为88.36%，合格碘盐食用率为81.03%。共采集儿童尿样31 883份，尿碘中位数为193.13 μg/L；尿碘中位数< 100 μg/L的县有1个，尿碘中位数在100 ~ 299 μg/L的县有150个。共采集孕妇家中食用盐15 572份，其中碘盐份数为14 260份，合格碘盐份数为13 363份。人口标化后碘盐覆盖率为90.10%，合格碘盐食用率为83.54%。共采集孕妇尿样15 569份，尿碘中位数为164.86 μg/L，尿碘中位数< 150 μg/L的县有67个。结论:河北省儿童和孕妇的碘营养在省级水平是适宜的，但部分县儿童和孕妇有碘营养不足风险，今后碘缺乏病防治重点应该放在特需人群的碘营养监测上。

abstractsObjective:To master the iodine nutritional level of children aged 8-10 and pregnant women in non-iodine excess areas in Hebei Province, and provide scientific basis and targeted prevention and treatment strategies for prevention and treatment of iodine deficiency disorders.Methods:Iodine nutrition analysis was conducted in 162 counties (cities and districts, hereinafter referred to as counties) of Hebei Province in 2018. Each monitoring county was divided into 5 sampling areas according to east, west, south, north and middle locations. One township/street was randomly selected in each area, 1 primary school was selected in each township/street, and 40 non-boarding students aged 8-10 were selected from each primary school. In each monitoring county, 20 pregnant women were selected from each of the 5 townships/streets. Both children and pregnant women were collected samples for salt and urinary iodine (with a random urine sample) detection. The iodine content of salt was tested using the "General Test Method for Salt Industry-Determination of Iodine" (GB/T 13025.7-2012), and Sichuan salt and other fortified edible salt used the arbitration method. The urinary iodine content was tested using the "Arsenic-Cerium Catalytic Spectrophotometric Determination of Iodine in Urine" (WS/T 107-2006).Results:A total of 31 883 samples of edible salt were collected from children's homes in 162 counties, among which 28 539 were iodized salt, 26 456 were qualified iodized salt, the iodized salt coverage rate was 88.36% (after population standardization), and the qualified iodized salt consumption rate was 81.03% (after population standardization). A total of 31 883 urine samples were collected from children, with the median urinary iodine of 193.13 μg/L. There was one county with a median urinary iodine < 100 μg/L, and the median urinary iodine in 150 counties was 100-299 μg/L. A total of 15 572 salt samples of pregnant women were collected, among which the iodized salt samples were 14 260, the qualified iodized salt samples were 13 363, the iodized salt coverage rate was 90.10% (after population standardization), and the qualified iodized salt consumption rate was 83.54% (after population standardization). A total of 15 569 pregnant women were collected urine samples, the median urinary iodine was 164.86 μg/L, and the number of counties with a median urinary iodine < 150 μg/L was 67.Conclusions:Iodine nutrition of children and pregnant women is appropriate at the provincial level, but children and pregnant women in some counties are at risk of iodine deficiency. In the future, the prevention and treatment of iodine deficiency disorders should focus on the iodine nutrition monitoring of the special needs.