摘要目的:了解武汉市孕妇碘营养状况，为指导孕妇科学补碘、调整碘缺乏病防治策略提供依据。方法:2016年5月至2020年9月，在武汉市13个行政区，每个区按东、西、南、北、中划分5个片区，每个片区抽取1个乡镇（街道），每个乡镇（街道）抽取20名孕妇，采集其家中食用盐盐样及尿样，检测盐碘、尿碘含量。盐碘检测采用直接滴定法，川盐及其他强化食用盐采用仲裁法；尿碘检测采用砷铈催化分光光度法。按照不同年份，区域（中心城区、远城区），年龄[低龄（<25岁）、适龄（25 ~ 34岁）、高龄（≥35岁）]，孕期[孕早期（<13周）、孕中期（13 ~ 27周）、孕晚期（28 ~ 40周）]对盐碘及尿碘进行分析。结果:共采集孕妇家中食用盐盐样5 200份，盐碘中位数为24.41 mg/kg；其中，无碘盐32份，合格碘盐4 962份，不合格碘盐206份，碘盐覆盖率为99.38%（5 168/5 200），合格碘盐食用率为95.42%（4 962/5 200）。共检测孕妇尿样5 200份，尿碘中位数为161.24 μg/L。2016年的中心城区、孕早期、孕中期、低龄及高龄孕妇（141.74、149.00、132.34、135.17、121.00 μg/L），2017年的孕早期、孕中期及高龄孕妇（128.00、149.00、141.41 μg/L），2020年的孕中期及高龄孕妇（148.95、138.00 μg/L）尿碘均<150 μg/L，处于碘缺乏水平。结论:武汉市孕妇总体处于碘适宜水平，但接近适宜值下限，部分孕妇仍存在碘缺乏风险。需密切关注孕妇的碘营养状况，积极倡导其食用合格碘盐。

abstractsObjective:To understand the iodine nutrition status of pregnant women in Wuhan, and to provide a basis for guiding pregnant women to supplement iodine scientifically and adjust the prevention and control strategy of iodine deficiency disorders.Methods:From May 2016 to September 2020, each district of 13 administrative districts in Wuhan was divided into 5 areas according to east, west, south, north and middle. One township (street) was selected from each area, and 20 pregnant women were selected from each township (street). Edible salt and urine samples were collected to detect the contents of salt iodine and urinary iodine. Salt iodine was determined by direct titration, Sichuan salt and other fortified edible salt by arbitration method; urinary iodine was detected by arsenic-cerium catalytic spectrophotometry. Salt iodine and urinary iodine were analyzed according to different years, regions (central and far urban areas), age [low age (< 25 years old), appropriate age (25 - 34 years old), old age (≥35 years old)], and pregnancy [early pregnancy (< 13 weeks), middle pregnancy (13 - 27 weeks), and late pregnancy (28 - 40 weeks)].Results:A total of 5 200 edible salt samples from pregnant women's homes were collected, and the median salt iodine was 24.41 mg/kg. Among them, there were 32 non-iodized salts, 4 962 qualified iodized salts, and 206 unqualified iodized salts. The coverage rate of iodized salt was 99.38% (5 168/5 200), and the consumption rate of qualified iodized salt was 95.42% (4 962/5 200). A total of 5 200 pregnant women's urine samples were tested, and the median urinary iodine was 161.24 μg/L. Urinary iodine < 150 μg/L was found in central urban area, early pregnancy, middle pregnancy, low age and old age pregnant women in 2016 (141.74, 149.00, 132.34, 135.17, 121.00 μg/L); in early pregnancy, middle pregnancy and old age pregnant women in 2017 (128.00, 149.00, 141.41 μg/L); and in middle pregnancy and old age pregnant women in 2020 (148.95, 138.00 μg/L), which was at iodine deficiency level.Conclusions:Pregnant women in Wuhan are generally at iodine appropriate level, but close to the lower limit of the appropriate value, some pregnant women are at risk of iodine deficiency. It is still necessary to pay close attention to iodine nutrition status of pregnant women, and advocate pregnant women to eat qualified iodized salt actively.