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换一批TGFβ and Hypoxia Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
TGFβ and Hypoxia Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
摘要篇首： Breast cancers frequently metastasize to bone, a site of hypoxia and high concentrations of active TGFβ. Skeletal metastases involve interactions between tumor and bone cells driven by locally secreted proteins, many of which are increased by hypoxia and TGFβ.
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主题词
骨和骨组织(Bone and Bones)转化生长因子β(Transforming Growth Factor beta)低氧(Hypoxia)内驱力(Drive)乳腺肿瘤(Breast Neoplasms)
分类号
R73
栏目名称
C 大会报告者简介及摘要
发布时间
2009-07-29
- 浏览127
- 被引1
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