摘要目的 了解高脂血症性急性胰腺炎(HL-AP)的临床特点,提高对HL-AP的认识.方法 回顾159例急性胰腺炎(AP)患者资料,其中18例HL-AP、141例为其他病因的AP,对两组的年龄、甘油三酯(TG)、血钙(Ca2+)、血糖(GLU)、CT严重指数(CTSI)、急性生理和慢性健康评分(APACHE Ⅱ)及合并糖尿病酮症酸中毒(DKA)的发生率进行比较,并将HL-AP组的TG值与上述指标进行相关分析.结果 HL-AP组与对照组相比除Ca2+明显下降外,TG、APACHE Ⅱ评分、CTSI、GLU和合并DKA的发生率均显著性增高(均P<0.05).HL-AP组TG值和APACHE Ⅱ评分、CTSI均呈正相关(均P<0.05);TG值和Ca2+水平存在直线负相关r=-0.795,P<0.01)关系.结论 HL-AP临床并不少见,其血清TG水平与HL-AP的病变程度呈正相关,且病情较严重,应重视对HL-AP的早期诊断和治疗.

abstractsObjective To study the clinical features of hyperlipidemic acute pancreatitis(HL-AP)and to en-hyance the awareness of diagnosis and treatment of HL-AP. Methods To Retrospective analyse 159 cases with acute pancreatitis (AP), of which 18 cases of HL-AP(HL-AP group), 141 cases of other causes of AP(non-HL-AP group),to compare the age, triglyceride (TG), calcium (Ca2+) levels, blood glucose (GLU), CT severity index (CTSI), acute physiology and chronic health evaluation (APACHE Ⅱ) and the the incidence of combined diabetic ketoacidosis (DKA) in two groups,correlative analysis between TG in HL-AP group and the above-mentioned indicators was car-rird out. Results In addition to significantly decreased Ca22+ , TG, APACHEⅡ score, CTSI points, GLU, and the combined incidence of DKA were significantly increased (both P < 0. 05) in HL-AP group when compared with the control group,TG and APACHE Ⅱ score, CTSI score were positively correlated(P < 0. 05),TG and the Ca2+ was negatively correlated (r = - 0. 795, P < 0. 01). Conclusion HL-AP is not uncommon, mainly patients are young and middle-aged with positively correlated between serum TG levels and the HL-AP lesions, and the condition is more seri-ous and,we should pay attention to the early diagnosis and treatment of HL-AP, main treatment is non-surgical treat-ment.