摘要目的 探讨手术后谵妄患者应用杜氟合剂治疗的剂量和效果.方法 85例麻醉苏醒期和术后1～2 d出现谵妄的患者,应用杜氟合剂治疗,并对其剂量和效果进行回顾性统计分析.结果 应用1/4剂(一剂杜氟合剂为哌替啶100 mg和氟哌啶醇5 mg)杜氟合剂治愈者9例,1/2剂治愈者61例;谵妄再发作时10例追加1/4剂,5例追加1/2剂,均治愈.给药后血压均出现下降,但均在正常范围内,脉搏血氧饱和度低于95%者17例.结论 杜氟合剂能有效治疗麻醉苏醒期和术后出现的谵妄,但需从低剂量开始,并注意其对呼吸的影响.

abstractsObjective To explore the dose and effects of mixtures of pethidine and haloperidol for Postoperative Deliri-um. Methods Retrospective analysis was conducted on treatment dose and effects of 85 cases of patients with deliri-um during narcotic awake period or 1 day to 2 days after operation by mixtures (haloperidol with pethidine) from 2005 to 2006 in Affiliated Hospital of Hainan Medical College. Results 1/4 dose of mixture (pethidine 100 mg and haloperidol 5 mg) cured 9 patients, 1/2 dose of mixture cured 61 cases, we add 1/4 dose of mixture when 10 cases occurred delirium again ,5 cases added 1/2 dose of mixture again, all were cured. After administration ,aublood pres-sure declined all, but all were within normal range, the 17 cases's pulse oxygen saturation is less than 95%, Conclu-sion The mixture (haloperidol with pethidine) can be effective treatment for delirium during awake period of general anesthesia or after operation. However, application of low dose therapy from the beginning, and attention to its impact on respiration.