摘要目的：探讨阿德福韦酯联合安络化纤丸治疗慢性乙型肝炎肝硬化的临床治疗疗效。方法收治的98例慢性乙型肝炎肝硬化患者按照随机数字表法分为两组，对照组49例患者给予阿德福韦酯治疗，而观察组49例患者给予阿德福韦酯联合安络化纤丸进行治疗，观察两组的治疗效果。结果观察组总有效率为92．9％，对照组总有效率为69.4％，观察组总有效率明显高于对照组，两组差异有统计学意义（χ2＝9．37， P＜0．05）；观察组与对照组治疗前的ALT（丙氨酸氨基转移酶）和HA（透明质酸）以及A／G（白蛋白／球蛋白）比较差异无统计学意义，t值分别为0．2131、1．2122、0．4032，均P＞0．05；治疗后两组的ALT和HA以及A／G较治疗前有明显的改善，观察组的改善程度明显的优于对照组的情况，差异有统计学意义，t值分别为11．3021、9．0121、7．3124，均P＜0．05。结论临床中对于慢性乙型肝炎肝硬化患者给予阿德福韦酯联合安络化纤丸治疗具有较好的治疗效果，并有效的改善患者的临床症状，有效地改善患者的肝脏功能，从而提高患者肝脏排毒功能，提高临床治疗效果，值得临床中应用与推广。

abstractsObjective To explore the clinical effect of adenovirus dipivoxil combined with Anluohuaxian pill in the treatment of chronic hepatitis B cirrhosis .Methods 98 patients with chronic hepatitis B liver cirrhosis were randomly divided into the two groups .49 cases in the control group were treated with adenovirus dipivoxil ,and 49 ca-ses in the observation group were given adenovirus dipivoxil combined with Anluohuaxian pill .The clinical effect of two groups was observed .Results The total effective rate of the observation group was 92.9%,which was significant-ly higher than 69.4% of the control group (χ2 =9.37,P<0.05).Before treatment,the alanine aminotransferase (ALT),hyaluronic acid (HA) and albumin/globulin (A/G) between the observation group and the control group had no significant differences (t=0.213 1,1.212 2,0.403 2,all P>0.05).After treatment,the ALT,HA and A/G of the two groups were significantly improved compared with those before treatment ,the improvement of the observation group was better than control group ,the difference was statistically significant ( t=11.302 1,9.012 1,7.312 4,all P<0.05).Conclusion In clinical practice,adenovirus dipivoxil combined with Anluohuaxian pill in the treatment of patients with chronic hepatitis B cirrhosis has good therapeutic effect ,it can improve the clinical symptoms and pa-tients'liver function ,so as to improve the liver detoxification function and the clinical treatment effect ,which worthy of clinical application and promotion .