摘要目的：探讨非小细胞肺癌患者发生淋巴结转移与肿瘤体积大小的关系，了解肺癌淋巴转移的规律，为临床手术及后续治疗提供依据。方法选取住院并行手术切除肺叶的非小细胞肺癌患者180例，对患者的临床资料以及切除肿瘤的体积大小、淋巴结转移情况进行回顾性分析，探讨患者淋巴结转移与肿瘤体积的关系。结果180例患者中淋巴结转移率为37．20％，其中肺门、肺内淋巴结转移率为11．02％，纵隔淋巴结转移率为10．95％。T1a 期淋巴结转移率，肺门、肺内淋巴结转移率以及纵隔淋巴结转移率分别为13．21％、15．09％、13．21％，T1b 期分别为38．09％、35．71％、28．57％，T2a 期分别为44．44％、37．78％、31．11％，T2b 期分别为64．26％、57．14％、53．57％，T3期期分别为58．33％、66．67％、41．67％，T1a 的淋巴结转移率、肺门、肺内淋巴结转移率以及纵隔淋巴结转移率与 T1b、T2a、T2b 及 T3分期的患者差异均有统计学意义（χ2＝5．363、6．175、4．372，8．778、5．363、9．631，7．936、9．631、20．463，7．521、6．175、4．387，均 P ＜0．05），T1b 的淋巴结转移率以及肺门、肺内淋巴结转移率与 T2b 差异均有统计学意义（χ2＝12．353、4．585，均 P ＜0．05）。结论对于非小细胞肺癌患者而言，肿瘤大小与淋巴结转移存在正相关，即肿瘤越大，淋巴结转移的可能性就越大。

abstractsObjective To discuss the relationship between the incidence of lymph node metastasis and tumor size in patients with non small cell lung cancer,and to provide evidence for clinical operation and follow -up treat-ment.Methods 180 patients with non small cell lung cancer who were hospitalized and recieived Lobectomy opera-tion were selected,the clinical data of patients and resection of tumor size,lymph node metastasis were retrospectively analyzed,and then the relationship between the lymph node metastasis and tumor volume was investigated.Results 180 cases of patients with lymph node metastasis rate was 37.20%,in which hilar lymph node metastasis rate was 11.02 percent and mediastinal lymph node metastasis rate was 10.95%.Lung lymph node metastasis rates in lymph node metastasis,hilar and mediastinal lymph node metastasis of T1a were 13.21%,15.09% and 13.21%;those of T1b period were 38.09%,35.71% and 28.57%;of T2a period were 44.44%,37.78% and 31.11%;of T2b period were 64.26%,57.14% and 53.57%;and those of T3 period were 58.33%,66.67% and41.67%.Lymph node metastasis,hilar and mediastinal lymph node metastasis in lung lymph nodes transfer rate with patients of T1a had significantly differences compared with patients of T1b,T2a,T2b and T3 stage.(χ2 =5.363,6.175,4.372,8.778, 5.363,9.631,7.936,9.631,20.463,7.521,6.175,4.387,all P <0.05).Hilar lymph node metastasis and lung metastases of T1b and T2b had a significant difference (χ2 =12.353,4.585,all P <0.05).Conclusion For non -small cell lung cancer,tumor size is positively correlated with lymph node metastasis and the greater the tumor size, the greater the likelihood of lymph node metastasis.