摘要目的：观察硬膜外自控镇痛用于剖宫产术后疼痛的效果及对细胞因子水平的影响。方法选取剖宫产产妇80例为研究对象，将其根据随机数字表法分为对照组（哌替啶肌内注射组）40例和观察组（硬膜外自控镇痛组）40例，然后将两组患者产前与产后12 h、24 h、48 h 疼痛评分、血清疼痛指标及细胞因子进行统计及比较。结果观察组干预后12 h、24 h 及48 h 的轻度疼痛者比例分别为75．00％、80．00％及87．50％，其均高于对照组（χ2＝6．542、732、6．141，均 P ＜0．05），血清疼痛因子及细胞因子水平均低于对照组（均 P ＜0．05）。结论硬膜外自控镇痛对剖宫产产妇术后疼痛应激指标及细胞因子的影响较大，可有效改善剖宫产产妇的产后不适感及炎性状态。

abstractsObjective To observe the effect of patient -controlled epidural analgesia for the postoperative pain and influence for the cytokines of delivery women with caesarean section.Methods 80 delivery women with caesarean section were selected as research objects,and they were divided into the control group(pethidine by intra-muscular injection group)of 40 cases and the observation group(patient -controlled epidural analgesia group)of 40 cases according to the random number table.Then the pain score,serum pain indexes and cytokines of the two groups before the delivery and at 24h and 48h after the delivery were analyzed and compared.Results The mild pain rates of the observation group at 12h,24h and 48h after the delivery were respectively 75.00%,80.00% and 87.50%,which were all higher than those of the control group(χ2 =6.542,732,6.141,all P <0.05),the serum pain indexes and cytokines were all lower than those of the control group too,the differences were statistically significant (all P <0.05).Conclusion The influence of patient -controlled epidural analgesia for the postoperative pain tress indexes and cytokines of delivery women with caesarean section are great,and it can effectively improve the discomfortableness and inflammatory state of delivery women after the the delivery.