摘要目的 探讨2型糖尿病患者颈动脉内膜中层厚度(IMT)与血清脂联素(adiponectin)相关性.方法 对65例2型糖尿病患者和60例正常对照者,分别测定血清脂联素(adiponectin)及生化指标,采用超声测定IMT,比较两组间血清脂联素(adiponectin)及IMT水平.对2型糖尿病患者采用多元回归分析,统计颈动脉IMT和血清脂联素(adiponectin)之间的关系.结果 血清脂联素(adiponectin)与2型糖尿病患者颈动脉IMT增厚有关.结论 2型糖尿病患者颈动脉IMT与血清脂联素(adiponectin)呈正相关,提示2型糖尿病患者血清脂联素(adiponectin)可协助诊断冠心病.

abstractsObjective To observe the Association of intima-media thickness of common carotid artery with the level of serum adiponectin in type 2 diabetic patients.Methods The intima-media thickness(IMT) of common carotid artery was measured using B-mode ultragonography in 65 patients with type 2 diabetes mellitus (DM) and 60 normal controls.The serum levels of adiponectin and biochemical index were measured respectively.In the tye 2 diabetes mellitus group,probable risk factors were analysed by multiple stepwise regression.Resuits Adiponeetin was risk of thickened IMT in type 2 DM.Conclusion The IMT is correlated with the level of adiponectin may be used as a reference index for the prediction of coronary artery disease.