摘要目的 探讨多发性消化性溃疡的发病及诊治情况.方法 回顾性分析本院2007-2008消化内科胃镜检查等临床资料.结果 2007、2008年消化性溃疡检出率分别为23.57%;25.19%,差异无统计学意义(P>0.05).多发性溃疡各占6.41%;6.33%,差异无统计学意义(P>0.05).2007、2008年多发性消化性溃疡损害因素HP感染率分别为80.77%;82.76%,药物因素各占42.31%;37.93%,血清胃泌素平均值分别(139±21.3),(141±20.9),差异均无统计学意义(P>0.05).并发症出现率分别为30.77%;37.93%,差异无统计学意义(P>0.05).两种不同治疗方法患者症状缓解、溃疡愈合不良反应比较无统计学差异(P>0.05).HP根除率分别71.43%;95.24%,差异有统计学意义(P<0.05).结论 多发性消化性溃疡在消化性溃疡中的发病率相对稳定,HP、NSAID与胃泌素仍是最重要的致病因素,以埃索美拉唑+左旋氧氟沙星为中心的j联疗法明显优于传统的治疗方法.

abstractsObjective To explore the Morbidity, Diagnosis and Treatment of Multiple Peptic U]cer. Methods We retrospectively analyzed the gnstroscopy and other clinical data of department of Digestion Medi- cien of our hospital sine 2007 ～ 2008. Results 2007,2008 peptic ulcer in detection rates were 23. 57% ; 25. 19%, the difference was not significant (P > 0. 05 ). Multiple ulcers for Each 6. 41% ; 6. 33%, there was no significant difference ( P > 0. 05 ). 2007,2008 damage factor in peptic ulcer multiple HP infection rates were 80. 77% ; 82. 76% ,Drug factors42. 31% ; 37. 93%, ,the average serum gastrin 139 ± 21.3; 141 ± 20. 9,statis-ileal significance( P > 0. 05 ). Complication rate of 30. 77% ; 37. 93%, the difference was not significant( P > 0. 05 ). Two different treatment methods in patients with symptoms, ulcer healing compared adverse reactions was no significant difference( P > 0. 05 ). HP eradication rates were 71.43% ; 95.24%, the difference was statisti-cally significant ( P < 0. 05 ). Conclusion Multiple peptic ulcer in the incidence of peptic ulcer is relatively sta-ble, HP, NSAID and Gastrin is still the most important pathogenic factors, esomeprazole + Levofloxacin triple-centric therapy was superior to the traditional method of treatment.