摘要目的 通过二甲双胍对精神分裂症患者糖尿病前期的早期干预,延缓或降低抗精神病药治疗中糖尿病的发生.方法 首发未使用抗精神病药物的精神分裂症患者65例,按糖调节受损的程度分为空腹血糖受损(IFG)和糖耐量受损(IGT)两大组,随机将IFG组和IGT组分为实验组和对照组.对IFG和IGT实验组患者进行小剂量二甲双胍治疗,治疗前后分别测量血糖、血脂、血压、体重指数、糖化血红蛋白,对结果 进行统计分析.结果 二甲双胍对精神分裂症患者糖尿病前期的早期干预可以降低抗精神病药治疗中糖尿病发生的风险.

abstractsObjective Mefformin in patients with schizophrenia through pre-diabetes early intervention to postpone or reduce the antipsychotic treatment of diabetes. Methods The first unused antipsychotics 65 ca-sea of patients with schizophrenia. Impaired glucose regulation in accordance with the extent of IFG and IGT is divided into two groups. Random IFG group and IGT will be divided into experimental and control groups. IFG and IGT for the experimental group, patients with low-dose mefformin therapy. Before and after treatment patients were measured blood glucose, blood lipids, blood pressure, body mass index, glycosylated hemoglobin, on the re-suits of statistical analysis. Results Mefformin in patients with schizophrenia early intervention pre-diabetes can reduce the anfipsychotic treatment of diabetes risk.