摘要目的 探讨影响致病菌对抗生素敏感的重症社区获得性肺炎(Severe community acquired Pneumonia,SCAP,下同)患者预后的其它因素.方法 参照2006年SCAP诊断标准,回顾性分析2004年7月至2008年12月致病菌对抗生素敏感的45例SCAP患者的临床资料.结果 应用头孢三代+大环内酯类组死亡风险高于其它组；死亡组低蛋白血症例数多于存活组；酗酒合并基础疾病组和单纯酗酒组的死亡率均高于其他两组,差异均具有统计学意义(P＜0.05).结论 为改善SCAP患者的预后,除积极应对可逆因素外,还应强调对相对不可逆因素的一级预防.

abstractsObjective To investigate the prognosis factors on SCAP patients which are sensitive to the antibiotics.Methods According to the diagnosis standard of SCAP in 2006，45 SCAP patients in our hospital from july 2004 to December 2008 were analyzed retrospectively，of which the pathogens are sensitive to the antibiotics.Results The mortality risk of using the third generation cephalosporins plus macrolides was higher than that of others；The number of the samples with hypoproteinemia in death group is larger than that of survival group；The mortality rate of alcoholism combined concomitant disease group and simple alcoholism group are both higher than that of others.Conclusion To improve the prognosis of SCAP patients，we should eliminate the interfered factors positively，and we shall emphasize primary prevention of the factors.