血管内皮生长因子与子宫内膜透明细胞癌预后相关性研究
The correlated study on VEGF and the prognosis of uterine endometriai clear cell carcinoma
摘要目的 研究子宫内膜透明细胞癌ECCC(uterine endometrial clear cell carcinoma,ECCC)组织中血管内皮生长因子(vascular endothelial growth factor,VEGF)和血小板源性生长因子(platelet-derived endothelial cell growth factor PD-ECG/TP)的表达,从肿瘤新生血管的形成方面来探讨ECCC的预后相关因素.方法 应用免疫组化法检测24例ECCC组织中VEGF、TP的表达,根据VEGF表达情况分成高表达组和低表达组,分析两组患者的生存差异.结果 在ECCC组织中,VEGF/TP均有较高的表达,两组患者的生存差异有统计学意义.结论 低表达组患者的生存时间长于高表达组.
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abstractsObjective To determine and analyze the relationship between VEGF/TP expression and ECCC patients'survival time.Mcthods 24 cases of ECCC were analyzed by immunohistechemistry.We separated the patients into high and Low expressions of VEGF group Results low or high expressions of VEGF and TP has a significant influential difference for the patients'survival time.Conclusion There is a close relationship between VEGF expression and prognosis of ECCC
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