摘要目的 探讨重型颅脑损伤后血糖变化与预后的关系.方法 对116例重型颅脑损伤患者(GCS≤8分),以入院时GCS评分判定病情分成3～4分组(34例),5～6分组(38例),7～8分组(44例),入院后12 h内取静脉血测定空腹血糖值进行回顾性分析,观察血糖浓度与GCS评分的关系.并对血糖变化与预后(良好、差、死亡)进行分析.结果 重型颅脑损伤患者血糖明显增高,GCS评分三组间血糖值有显著性差异(P＜0.01),人院时GCS评分越低,血糖越高,预后越差.结论 高血糖可严重影响颅脑损伤的预后,及时有效地控制血糖,能改善患者的神经功能及预后,提高生存质量.

abstractsObjective To explore the effect of blood glucose( BG)fluctuation by severe type craniocerebral injury on the prognosis. Methods Retrospective reviews were done to 116 patients of gravis type craniocerebral injury whose GCS Score ≤ 8. According to the GCS Score at admission, 116 patients were divided into three groups ,34 cases for GCS Score3-4 scores, 38 cases for GCS Score5-6 scores,44 cases for GCS Score7-8scores,median cubical vein blood were taken to check fasting plasma glucose within 12 hours at admission, to observe the relationship between the blood glucose concentration and GCS Score. The blood glucose fluctuation and prognosis were analyzed by the discharge condition, including improvement, poor treatment and death. Results The BG value was higher than the normal reference value after the patients suffered from the craniocerebral injury. The blood glucose values were significantly different in the three groups ( P ＜0.01 ) . The lower the GCS Score,the higher the BG value,the worse the prognosis. Conclusion Hyperglycemia can seriously affect the prognosis of patients with craniocerebral injury, if the hyperglycemia was controlled promptly and effectively, the nervous function and prognosis will be improved, and the quality of lifebe enhanced.