多发伤患者抵抗素与ISS、APACHEⅡ 评分的相关性研究
Study on serum levels changes of resistin and its relations to ISS,APACHE Ⅱ score in patients with multiple trauma
目的 研究多发伤后患者血清抵抗素的水平变化,并探讨其与ISS、APACHEⅡ评分的相关性.方法 测定106例多发伤患者伤后第1、3、7天的血清抵抗素水平,同时评定其ISS、APACHEⅡ分值.了解抵抗素水平变化与ISS、APACHEⅡ分值的相关性.结果 分别以ISS≤16分组和>16分组及以APACHEⅡ≤20分组和>20分组,两组之间伤后第3、7天抵抗素水平与APACHEⅡ明显相关(P<0.01).而创伤后第1天,抵抗素水平与ISS、APACHEⅡ评分无显著相关性(P>0.05).结论 伤后第3、7天的抵抗素水平与ISS、APACHEⅡ评分显著相关,常规检测创伤后血清抵抗素水平并联合评定ISS、APACHEⅡ评分有助于对创伤后脏器功能不全的预测.
更多Objective To study the change of serum resistin in patients with multiple traumas,and to determine its relationship to ISS and APACHE Ⅱ.Methods The levels of serum resistin of 106 cases on the lst,3rd and 7th day after trauma was observed respectively ,and then its relationship to ISS and APACHE Ⅱ was estimated.Results Between the 2 group of ISS > 16 or ≤ 16,and APACHE Ⅱ> 20 or ≤20,the level of resistin on the 3rd and 7th day was closely correlated with ISS and APACHE Ⅱ(P < 0.01),while which showed no correlations with ISS and APACHE Ⅱ on the 1 st day after trauma(P > 0.05).Conclusion The level of resistin on the 3rd and 7th day closely correlated with ISS and APACHE Ⅱ ,which is probably helpful to predict the incidence of organ disfunction after multiple trauma.
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