检索历史 清除

目的：探讨内镜全层切除术（EFR）对胃固有肌层间质瘤的治疗价值。方法选取2011年2月至2013年8月于烟台毓璜顶医院消化内镜中心行胃镜检查发现并经超声胃镜、CT 或MRI 检查，提示为胃固有肌层间质瘤患者18例，在气管插管全麻下行 EFR 治疗，术后随访评价其疗效及安全性。结果经 EFR 治疗的18例患者，病变均一次性完整切除。切除肿瘤最大直径1.2～3.0 cm，平均最大直径为1.8 cm。EFR 手术时间为45～120 min，平均手术时间为85.5 min。术后病理证实2例位于胃体的肿瘤为平滑肌瘤，其余均为间质瘤。术后均未出现出血、腹膜炎等并发症。术后随访1～12个月，创面愈合良好，病变均无残留或复发。结论 EFR 治疗胃固有肌层间质瘤安全、有效，具有创伤小、整体切除率高的优点，具有良好的临床推广价值。

Objective To study the therapeutic value of endoscopic full-thickness resection for gastric stromal tumor. Methods From February 2011 to August 2013, 18 cases of patients with gastric stromal tumors originating from the muscularis propria layer were detected by endoscopic ultrasonography, CT and MRI in Yantai Yuhuangding Hospital, then treated with endoscopic full-thickness resection(EFR) after intubation anesthesia. The patients were followed up with gastrocope for evaluation of therapeutic effect and safty. Results EFR was successfully accomplished to remove all tumors in 18 patients. The size of tumors ranged from 1.2 to 3.0 cm ( mean 1.8 cm) in diameter. The mean procedure time was 85.5min(45 ~ 120min).Except in 2 leiomyomas,pathological examination confirmed gastric stromal tumor in 16 cases. None of patients had occurred bleeding, peritonnitis and other complications after EFR. Thereafter, all patients were followed up with gastrocope after 1 ~ 12 months. Lesions healed well, no residual or recurrence. Conclusion EFR is effective and safe for patients with gastric stromal tumors originated from muscularis propria layer and has the advantage of less invasive treatment and higher tumor resection rate. It should be popularized in the future.