摘要目的：探讨尼莫地平治疗高血压性脑出血过程中，对降低外周脑血管阻力（R）及提高近期治疗效果的意义与价值。方法选择20011年1月至2014年1月滨州市中心医院收治的高血压性脑出血患者208例，随机将其分成试验组与对照组，各104例，对照组行常规治疗，试验组在对照组治疗的基础上加用尼莫地平，采用静脉滴注方式，缓慢静滴，尼莫地平使用剂量为10 mg/d，滴注速度为1～3 mg/h。随后对两组患者的脑循环动力学参数（CVHI）进行检测，比较两组治疗前后平均血流速度（Vmean）、平均血流量（Qmean）、水肿面积与血肿体积、外周脑血管阻力（R）、临界压力值（CP）、神经功能缺损评分（NIHSS评分）、日常生活活动能力评分（BI评分），并对比两组治疗效果。结果治疗前与治疗后相比，两组患者的Qmean值均有所提高，但试验组较对照组升高明显（P<0.05）。两组Vmean值均有所提高，但两组差异不具有统计学意义（P>0.05）；两组患者R及CP值均有所降低，但试验组较对照组降低明显（P<0.05），两组患者水肿面积与血肿体积相比，差异无统计学意义（P>0.05），试验组NIHSS评分降低明显（P<0.05）、BI评分增加明显（P<0.05），试验组治疗显效率85.58%，对照组显效率59.03%，试验组显著提高，差异具有统计学意义（P<0.05）。结论高血压性脑出血应用尼莫地平治疗，副作用小，疗效可靠，且可降低脑血管阻力，增加脑血流量，对提高近期疗效有着非常重要的意义及价值，值得推广应用。

abstractsObjective To explore nimodipine treat high blood pressure in the process of cerebral hemorrhage,to reduce the peripheral cerebral vascular resistance (R) and the recent treatment ofthe meaning and value. Methods Choose from January 2009 to January 2012 to our hospital treatment forpatientswithhypertensive hemorrhage in 208 cases,Theclinicaldata of the retrospective analysis, Can be divided into the experimental group and the random control group, the 104 cases, The control group received conventional treatment, The experimental group in the control group the foundation of treatment combined with nimodipine, Nimodipine the dose of 10 mg/d, Drip speed for 1-3 mg/h. Detection cerebral circulation dynamic parameters (CVHI), Compared between the two groups before and after treatment the mean blood flow velocity (Vmean), average blood flow (Qmean), edema area and the week outside hematoma volume, cerebral vascular resistance (R), the critical pressure value (CP), BI (Barthel index) score, NIHSS (stroke rating scale) score. Results Two sets of patients Qmean value are improved, but the control group rise is obvious (P<0.05). Two groups of Vmean value are improved (P>0.05);Two groups of patients R and CP values are reduced, but the lower than the control group obvious (P<0.05), two groups of patients edema area and compared hematoma volume (P>0.05), and the lower NIHSS scores significantly (P<0.05), BI score increase obviously (P<0.05), and the treatment were 85.58%and significant efficiency, and the 59.03%significant efficiency increased significantly (P<0.05). Conclusion Hepertensive cerebral hemorrhage application nimodipine treatment, small side effects, and the results were reliable, and can reduce cerebral vascular resistance, increase blood flow to the brain, to improve the short-term curative effect has a very important significance and value, popularization.