摘要目的：研究发现红细胞分布宽度（RDW）与心力衰竭（HF）的程度相关。该研究的目的是评价基线入院时RDW对慢性心力衰竭（CHF）程度、多次住院的预测价值，并与其他血液学和生化学指标进行比较。方法选择2012年1月至2015年4月威海市中心医院收治的179例CHF患者的临床资料进行回顾性研究，其中NYHAⅠ级44例、Ⅱ级39例、Ⅲ级41例、Ⅳ级55例。用受试者工作特征曲线（ROC）分析确定最佳的Cut-off值和预测价值。结果 RDW 在Ⅲ级（14.3±2.3）%和Ⅳ级（14.3±1.7）%较Ⅰ级患者（12.9±0.8）%显著升高（P<0.01）。RDW和N-末端脑钠肽前体（NT-ProBNP）预测Ⅳ级CHF的ROC曲线下面积（AUC）分别是0.817、0.840。结论 RDW对Ⅳ级HF的预测价值与NT-proBNP相当。

abstractsObjective Red cell distribution width (RDW) has been shown to be associated with degree of chronic heart failure (CHF). This was a retrospective study that characterized predictive values of baseline RDW to assess severity of CHF, repeated admission. Methods Hematological and biochemical parameters were obtained from 179 patients with New York Heart Association (NYHA) CHF classⅠ(n=44),Ⅱ(n=39),Ⅲ(n=41), andⅣ(n=55). Receiver operator characteristic (ROC) curves were used for assessing predictive values. Results RDW increased significantly in classⅢandⅣcompared with classⅠ(14.3±2.3%and 14.3±1.7%vs. 12.9±0.8%, P<0.01). Areas under ROCs (AUCs) of RDW, N-terminal prohormone brain natriuretic peptide (NT-ProBNP) for class IV HF were 0.817 and 0.840. Conclusions RDW increased significantly in classⅢandⅣpatients.