摘要目的分析胃肠间质瘤（GIST）的临床特点及治疗方法。方法对2000年7月至2015年9月在洛阳市第二中医院外科住院经手术病理证实的86例GIST患者的临床资料进行回顾性分析。结果肿瘤发生在食道2例，胃部43例，十二指肠1例，小肠21例，结肠5例，直肠2例，盆腔6例，腹膜后6例。行腹腔镜下胃部肿瘤切除26例，结肠5例；55例行开腹手术，其中6例因肿瘤广泛转移无法完整切除，行局部切除或者取活检，49例完整切除肿瘤。无手术死亡病例。63例患者获随访，定期检查，10例术后复发，其中8例腹腔转移。结论外科手术是治疗GIST的主要方法，甲磺酸伊马替尼靶向治疗能够进一步改善GIST的预后。

abstractsObjective To analyze the clinical characteristics and treatment of gastrointestinal stromal tumors(GIST). Methods The Clinical data of 86 patients of GIST proved pathologically admitted from July 2000 to September 2015 at Department of surgery, the Second Traditional Medicine Hospital of Luoyang were analyzed retrospectively. Results The tumors originated respectively from the esophagus(n=2),stomach (n=43),duodenum(n=1),intestine(n=21),colon(n=5),rectum(n=2),pelvic cavity(n=6),peritoneum(n=6).Twenty-six cases of gastric and five cases of colon GIST were performed by laparoscopic lumpectomy.Fifty-five cases of GIST were performed by laparotomy.Six of them underwent palliative resection or biopsy because of extensive metastasis.Forty-nine cases were resected completely.There was no operative mortality.Sixty-three cases were followed-up.Recurrence and metastasis in ten patients,and eight of them were abdominal metastasis. Conclusion Surgical procedures is the first choice for treatment of GIST,imatinib mesylate targeted therapy can improve survival.