摘要目的 探讨加味旋覆代赭汤防治乳腺肿瘤化学治疗出现的消化道反应的疗效.方法 将78例接收乳腺肿瘤化学治疗的患者随机分为治疗组与对照组,每组39例.两组均给予帕洛诺司琼,治疗组化学治疗前1d加服加味旋覆代赭汤,连服7剂后比较疗效.结果 对照组未出现恶心及轻度恶心症状的患者共12例,治疗组未出现恶心及轻度恶心症状患者共24例,两组比较差异有统计学意义(P<0.01);对照组止呕有效率为35.9%(14/39),治疗组为61.5%(24/39),两组比较差异有统计学意义(P<0.05).结论 加味旋覆代赭汤能有效防治乳腺肿瘤化学治疗出现的消化道反应.

abstractsObjective To explore the effect of Jiaweixuanfudaizhe decoction in preventing and treating digestive tract reaction of chemotherapy for breast cancer. Methods A total of 78 patients with breast cancer who underwent chemotherapy were randomly divided into the treatment group and the control group, 39 cases in each group. Patients in both groups were given palonosetron, patients in the treatment group were given Jiaweixuanfudaizhe decoction 1 day before chemotherapy, and the effects after 7 continu-ous doses were compared. Results There were 12 cases did not appear nausea or mild nausea in the con-trol group and 24 cases did not appear nausea or mild nausea in the treatment group, and there was statisti-cally significant difference between the two groups(P<0. 01);the antiemetic efficiency in the control group was 35. 9%(14/39)and in the treatment group was 61. 5%(24/39), and there was statistically significant difference between the two groups(P<0. 05). Conclusion The Jiaweixuanfudaizhe decoction can effec-tively prevent and treat the digestive tract reaction of chemotherapy for breast cancer.