摘要目的:探讨常规开胸手术与电视胸腔镜手术治疗肺癌的临床效果。方法:选取2016年7月至2019年7月胶州市人民医院胸外科收治的80例肺癌患者，男44例，女36例，年龄(65.25±5.39)岁，年龄范围为41～72岁。按照不同手术治疗方式分为开胸组( n＝37)与胸腔镜组( n＝43)，比较两组患者围术期指标(下床活动时间、引流量、引流时间及住院时间)、炎症指标[白细胞介素-6(IL-6)、白细胞介素-8(IL-8)及白细胞介素-10(IL-10)]、术后并发症(伤口出血、肺不张及心房颤动)发生率。 结果:胸腔镜组下床活动时间[(1.06±0.43)d]较开胸组[(3.67±1.09)d]短，引流量[(254.46±17.54)ml]、引流时间[(2.19±0.45)d]及住院时间[(6.23±1.15)d]较开胸组[(510.93±30.56)ml、(6.47±2.40)d、(10.89±1.08)d]少，差异均有统计学意义( P<0.05)。开胸组术后的IL-6[(5.12±0.89)μg/L]、IL-8[(5.81±0.92)μg/L]及IL-10[(4.79±0.23)μg/L]水平较术前[(2.69±0.67)μg/L、(2.89±0.91)μg/L、(2.29±0.29)μg/L]升高，差异有统计学意义( P<0.05)。胸腔镜组术后与术前的IL-6、IL-8及IL-10水平比较，差异无统计学意义( P>0.05)。胸腔镜组并发症发生率[2.5%(1/43)]较开胸组[16.2%(6/37)]低，差异有统计学意义( P<0.05)。 结论:与常规开胸手术比较，采用电视胸腔镜治疗肺癌的患者可获得更好的围术期指标，不易引起严重的炎症反应，术后并发症发生率较低，安全性更高。

abstractsObjective:To investigate the clinical effects of conventional thoracotomy and video-assisted thoracoscopic surgery for lung cancer.Methods:A retrospective study was performed on 80 cases of patients with lung cancer who were admitted in Thoracic Surgery of Jiaozhou People′s Hospital from July 2016 to July 2019.There were 44 males and 36 females, aged(65.25±5.39)years old, ranging 41~72 years old.According to different surgical treatments, patients were divided into the thoracotomy group( n=37)and the thoracoscope group( n=43). Two groups of patients were compared with perioperative indicators(bed activity time, flow and drainage time and hospitalization time), inflammation index[interleukin 6(IL-6)and interleukin 8(IL-8)and interleukin 10(IL-10)], postoperative complications(bleeding, atelectasis and atrial fibrillation). Results:The duration of deactivation in the thoracoscopic group[(1.06±0.43)days]was shorter than that in the thoracotomy group[(3.67±1.09)days], the drainage volume[(254.46±17.54)ml], the drainage time[(2.19±0.45)days]and the length of stay[(6.23±1.15)days]were less than that in the thoracotomy group[(510.93±30.56)ml, (6.47±2.40)days, (10.89±1.08)days], and the differences were statistically significant( P<0.05). The levels of IL-6[(5.12±0.89)μg/L], IL-8[(5.81±0.92)μg/L]and IL-10[(4.79±0.23)μg/L]in the thoracotomy group were significantly higher than those before surgery[(2.69±0.67)μg/L, (2.89±0.91)μg/L, and(2.29±0.29)μg/L], with statistically significant differences( P<0.05). There was no significant difference in postoperative and preoperative levels of IL-6, IL-8 and IL-10 in the thoracoscopic group( P>0.05). The incidence of complications in the thoracoscopic group[2.5%(1/43)]was lower than that in the thoracotomy group[16.2%(6/37)], and the difference was statistically significant( P<0.05). Conclusion:Compared with conventional thoracotomy, video-assisted thoracoscopic surgery can obtain better perioperative index, and it is not easy to cause serious inflammatory reaction.The incidence of postoperative complications is lower and the safety is higher.