摘要目的:探讨双切口和单切口超声乳化白内障吸出术（PEA）对年龄相关性白内障患者（ARC）角膜的影响。方法:回顾性分析我院收治的行PEA治疗的ARC患者256例272眼的临床资料，其中137例150眼采用双切口PEA治疗设为对照组，119例122眼采用单切口PEA术治疗设为观察组，比较两组手术时间、累积释放能量（CDE）、超声时间、灌注液用量、裸眼视力、矫正远视力、手术相关性散光（SIA）、10 mm范围内角膜体积（10mm-CV）、中央角膜厚度（CCT）及角膜内皮细胞相关参数指标水平。结果:①两组手术时间、CDE、超声时间及灌注液用量比较差异无统计学意义（ P >0.05）；②观察组术后1周裸眼视力和矫正远视力均显著高于对照组（ P <0.05）；观察组术后1周角膜后表面SIA水平显著低于对照组（ P <0.05）；③观察组术后1周10mm-CV和CCT水平显著低于对照组（ P <0.05）；④观察组术后1、4、12周角膜内皮细胞损失率水平均显著低于对照组（ P <0.05）；观察组术后1周角膜内皮细胞平均面积水平均显著低于对照组（ P <0.05）。 结论:相较于双切口PEA，ARC患者采用单切口PEA联合人工晶状体植入术治疗可有效减轻角膜损伤，加快术后康复进程，并有助于改善视力。

abstractsObjective:To investigate the influence of double incision vs single incision phacoemusification aspiration(PEA) on cornea of patients with Age-related cataract (ARC) .Methods:Clinical data of 256 cases(272 eyes) of patients with Age-related cataract(ARC) by PEA combined with intraocular lens implantation were analyzed, retrospectively, including control group(150 eyes of 137 cases)with double incision PEA and observation group(122 eyes of 119 cases )with single incision PEA. The surgical time, cumulative dissipated energy(CDE), ultrasound time, perfusion volume, vision, surgically induced astigmatism(SIA), 10mm-cornea volume(10mm-CV), central corneal thickness(CCT) and corneal endothelial cell parameters of 2 groups were compared.Results:The difference in the surgical time, CDE, ultrasound time and perfusion volume between 2 groups were not significant( P >0.05). The levels of naked eye vision and corrected distant vision of 1 week after operation in observation group were significantly higher than that in. control group ( P <0.05). The levels of cornea anterior surface SIA of 1 week after operation in observation group was significantly lower than that in control group( P <0.05). The levels of 10mm-CV and CCT of 1 week after operation in observation group were significantly lower than that in control group( P <0.05). The levels of endothelial cells loss of 1 week, 4 weeks and 12 weeks after operation in observation group were significantly lower than that in control group ( P <0.05). The levels of corneal endothelial cell average size in 1 week after operation in observation group were significantly lower than that in control group ( P <0.05). Conclusions:Compared with double-incision PEA, single-incision PEA combined with intraocular lens implantation in the treatment of patients with ARC can effectively relieve corneal injury, accelerate the recovery process after operaiton and be helpful to improve visual quality.