换一批
换一批摘要篇首：In this special issue on hematology, four original research papers in the field of hematology from different institutions over China are presented. Zhao Chunhua et al from the National Key Laboratory of Hematology in Tianjing report on a primary CML cell model. By transfecting the bcr-abl gene into human CD34+ cells, a primary human hematopoietic stem/progenitor cell model was well developed with P210bcr/abl expression, elevation and relocation of P27kip, MDR-1 Pgp increment and other typical CML characteristics. This primary CML stem/progenitor cell model will be useful in studying the role of intracellular signal mechnisms in the pathogenesis of CML.
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