摘要目的阐述海洛因所致海绵状白质脑病的MR影像学表现及其诊断价值.方法收集11例具有吸食海洛因病史患者的MR影像资料.所有患者均进行MR检查,包括T1 WI、T2WI、Flair序列.结果所有患者(11例)幕上半球脑白质、小脑半球脑白质、内囊后肢及膝部、均见双侧、对称性沿脑白质分布的异常病变,其中6例患者胼胝体压部及膝部受侵,2例患者中脑中央见椭圆形病变.MR均表现为T1WI呈低信号,T2WI及Flair序列为高信号.以小脑半球白质受累最为严重,但其灰质核团未见受累.结论海洛因所致海绵状白质脑病具有典型的MR影像学表现,结合病史,MR诊断具有特异性.

abstractsObjective To elucidate the imaging characteristics of spongiform leukoencephalopathy induced by heroin and the diagnostic value of MRI examination.Methods Eleven cases of heroin addiction were examined by MRI.The sequences included T1-weighted imaging(T1WI),T2-weighted imaging(T2WI)and fast fluid-attenuated inversion recovery pulse sequence(Flair).Results Bilateral symmetrical lesions were located in the white matter of the cerebrum and cerebellum,the internal capsule in all cases,and the callosum in 6 cases.Elliptical lesions in the mesencephalon were found in two cases.These lesions were shown as hypointense signals on T1WI and hyperintense signals on T2WI and Flair's imaging.Cerebellar white matter suffered more severely,but the dentate nuclei were not invaded.Conclusion Heroin-induced spongiform leukoencephalopathy has characteristic patterns in MRI,which are very specific to this form of the disease.