摘要目的　探讨脑深静脉系统血栓形成的病因、临床表现及影像特征和在非急性期局部溶栓治疗的效果. 方法　回顾性分析了5例经DSA检查确诊为DCVT患者的病因、临床表现及影像特征和在非急性期溶栓治疗的结果. 结果　患者男3人,女2人,年龄22-49岁,病程1-7月,以发烧为诱因2例,原因不明3例,伴有颅内静脉窦4例.经介入放射局部溶栓和全身抗凝治疗后,神经系统症状和体征明显减轻,未见明显副作用. 结论　在诊断DCVT上,DSA比MRI要精确和敏感,且对治疗可进行评估；介入放射局部溶栓和全身抗凝治疗不仅在急性期对DCVT是安全、有效,而且在非急性期亦为一种积极治疗措施.

abstractsObjective To investigate the pathogenesis, clinical features, radiographic findings and therapeutic outcomes of non-acute intracranial deep venous thrombosis in adults. Methods Five patients who presented with increased intracranial pressure were examined with computed tomography, magnetic resonance and angiography, diagnosed as having non-acute intracranial deep venous thrombosis, and treated with thrombolytic therapy. They were reviewed retrospectively. Results There were 3 men and 2 women, aged from 22 to 49 years. Symptom duration ranged from 1 month to 7 months, and 4 of the 5 patients were associated with venous sinus thrombosis. Two patients developed cold and fever before the onset of disease, and 3 patients had no evident predisposing factors. After the infusion of thrombolytic and systemic anti-coagulant therapy, the neurological symptoms and signs of the patients were alleviated. Conclusions Digital subtraction angiography (DSA) is more sensitive and accurate than MRI on diagnosing intracranial deep venous thrombosis. It may play an important role in the assessment of the treatment of intracranial deep venous thrombosis. Thrombolysis and anticoagulation of intracranial deep venous thrombosis appears to be a safe and efficacious treatment not only in the acute stage but also in the non-acute stage.