摘要目的研究中国老年人体脂含量及其分布与多种心血管危险因子之间的相互关系.方法共135名中国老年人研究对象,年龄在60至65岁之间,均无明显心、肾、肝疾病.观察项目包括坐位血压、人体测量指标和空腹血浆生化参数.应用学生t检验来处理男女两组之间生化和人体测量指标的差异.结果男性比女性老年人较重(64.6±8.6 kg, 57.2±8.2 kg, P<0.001)、较高(1.65±0.06 m, 1.51±0.05 m, P<0.001),而且体脂主要分布在腹部 (腰臀比例 0.91±0.06, 0.88±0.07, P<0.05). 相比之下,女性老年人比较肥胖,平均体重指数大 (23.8±4.6 kg/m2, 25.0±3.5 kg/m2, P<0.05) 以及体脂百分含量高[26.3% (24.5%-28.1%) vs 37.2% (36.0%-38.9%), P<0.001].但是,尽管女性比男性老年人的体脂含量要高出11%,两组之间的血压、血脂、胰岛素抵抗参数或白蛋白-肌酐比值却没有显著差异. 结论尽管中国老年男性比女性要瘦一些,但是男性的中心性肥胖很可能更容易导致他们出现代谢异常.

abstractsObjective To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects.Methods One-hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student's t-test was used to compare the differences in biochemical and anthropometric markers between cohorts.Results Males were heavier (64.6±8.6, 57.2±8.2*!kg, P<0.001), taller (1.65±0.06, 1.51±0.05 m, P<0.001) and their greater body fat was predominantly deposited centrally (Waist-to-hip ratio, 0.91±0.06, 0.88±0.07, P<0.05). Females were more generally obese with increased body mass index (BMI, 23.8±4.6, 25.0±3.5 kg/m2, P<0.05) and percentage body fat [26.3% (24.5%-28.1%) vs 37.2% (36.0%-38.9%), P<0.001] than the males. However, despite an 11% higher proportion of body fat in females, no significant differences were identified in blood pressure, lipid profile, indices of insulin resistance or albumin-to-creatinine ratios.Conclusion It is likely that central adiposity contributes disproportionately to these metabolic disorders in males even though they are much leaner than elderly Chinese females.