检索历史 清除

目的功能性消化不良(FD)与社会心理因素的关系目前尚不清楚,本文探讨两者在国内人群中的发病率及其相互关系.方法采用问卷式调查方法,随机抽取1016例健康体检者进行一般情况调查及Zung自评抑郁量表(SDS)和焦虑量表(SAS)评定;同法对72例FD、84例器质性消化不良及197例其他器质性疾病的住院患者进行调查.结果 1016例健康体检者中,FD的检出率为23.5%、焦虑抑郁障碍为9.1%;FD合并焦虑抑郁(15.5%)较非FD(7.1%)明显高,(P<0.01);住院患者,FD合并焦虑抑郁(54.2%)较器质性消化不良(19.0%)和其他器质性疾病(28.9%)的异常明显高,(P<0.05),较健康人群FD患者并焦虑抑郁率(15.5%)亦明显高,(P<0.01);进一步的分析显示,社会心理异常是FD的高危因素.结论 FD和焦虑抑郁障碍在中国常见,两者间关系密切.

Objective To investigate the prevalence of functional dyspepsia (FD) and the psychological disorders in Chinese population and their relation. Methods A total of 1016 apparently healthy people (study population) randomly selected from population were interviewed. A general questionnaire, Zung self-rating depression scales (SDS), and anxiety scales (SAS) were given to each subject. Seventy-two inpatients with confirmed diagnosis of FD, 84 with organic dyspepsia, and 197 with other organic diseases were also studied. Results Among the study population, 23.5% had FD and 9.1% had disturbances of depression and/or anxiety. The prevalence of psychological disturbances in FD group (15.5%) differed significantly from that in non-FD group (7.1%, P<0.01). In the survey of inpatients, the rate of depression/anxiety in FD group (54.2%) was greater than that in organic dyspepsia group (19.0%) and other organic diseases group (28.9%), P<0.05, and was also significantly higher than that of the FD cases in the study population (15.5%), P<0.01. Further analysis showed that some psychosocial disturbances were risk factors of FD.Conclusion Both FD and depression/anxiety disturbances are common in China, and there is a link between them.