High risk genetic factor in Chinese patients with idiopathic male infertility:deletion of DAZ gene copy on Y chromosome

二维码有效期 120s

摘要篇首： Idiopathic azoospermia or oligozoospermia affects approximately 2%-4% of all married males. Recently studies have confirmed that the deletion of DAZ in AZFc region of Y chromosome may be one of the important genetic aetiologies of Caucasian male infertility. To determine the relationship between DAZ gene deletion and idiopathic male infertility in Chinese population, we analysed the DAZ gene copy number of AZFc region in patients with idiopathic azoospermia or oligozoospermia, as well as fertile Chinese men.

作者杨元 ^[1] 肖翠英 ^[1] 张思仲 ^[1] 张思孝 ^[2] 黄明孔 ^[3] 林立 ^[1] 学术成果认领

作者单位 Department of Medical Genetics, West China Hospital, Sichuan University, Chengdu 610041, China ^[1] Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, China ^[2] Institute of Sichuan Reproductive Health, Chengdu 610000, China ^[3]

关键词 deleted-in-azoospermia gene gene deletion infertility,male Y chromosome

分类号 R3

发布时间 2004-09-16

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