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Relationship between high-sensitivity C-reactive protein level and angiographical characteristics of coronary atherosclerosis

摘要篇首: Arole for inflammation has become well established over the past decade or more in theories describing the atherosclerotic disease process.1,2 From a pathological viewpoint, all stages, ie, initiation, growth, and complication of the atherosclerotic plaque,3,4 might be considered to be an inflammatory response to injury. Several prospective studies 5-7 recently showed that plasma high sensitivity C-reactive protein (hsCRP) levels, which are one of the markers of systemic inflammation, are a powerful predictor of future myocardial infarction and cardiac death among apparently healthy individuals. However, the association between the plasma hsCRP levels and the extent of coronary stenosis in subjects remains controversial. Some studies previously demon- strated such associations,8,9 whereas other could not found.10,11 Gensini's score assigns a severity score for a stenosed vessel depending on the degree of luminal narrowing and the importance of its location.12

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作者单位 Department of Cardiovascular Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China [1] Department of Chest Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China [2] Department of Clinical Laboratory, First affiliated hospital of Nanjing Medical University, Nanjing 210029, China [3]
分类号 R3
发布时间 2006-03-30
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中华医学杂志(英文版)

中华医学杂志(英文版)

2006年119卷4期

319-323页

SCIMEDLINEISTICCSCDCABP

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