摘要篇首： Muscle involvement in adults with hypothyroidism is common.At least 79% of patients with hypothyroidism have muscle weakness,cramps,and myalgia complaints~1.The patients with hypothyroidism do have myopathy rather than functional muscle diseases~2.Nonspecific muscle stiffness related to myalgia may be associated with serum muscle enzyme elevations.Serum creatine kinase (CK) elevation can be observed in 57%-90% of patients with hypothyroidism.Skeletal muscle is affected more profoundly in cases of overt hypothyroidism,less so when subclinical hypothyroidism is present~1.However,clinical muscular symptoms are not usually the chief complaint at presentation.More than 40% of patients with hypothyroidism also had neuromuscular complaints at the time of diagnosis~2.