换一批摘要Primary systemic amyloidosis is a relatively rare disease,caused when abnormal extracellular deposition of fibrillary protein builds up in a variety of target organs,such as heart,kidneys,lungs liver,and so forth.The symptoms of the disease are usually vague,while many kinds of auxiliary or laboratory examinations especially pathologic biopsy can provide a clue for the diagnosis.Here we described a case who had purpura-like lesions in the initial stage,followed by progressive malfunctions in the kidneys,the heart,the lungs,as well as the liver.The final diagnosis was primary systemic amyloidosis determined by skin pathologic biopsy.And the disease led to a fatal outcome within three months after the diagnosis.
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