摘要Background Tendon adhesion is one of the most common causes of disability following tendon surgery.Therefore,prevention of peritendinous adhesion after surgical repair of tendon is a major challenge.The aim of this study was to explore the possible application of a collagen membrane for the prevention or attenuation of peritendinous adhesions.Methods Sprague-Dawley (SD) rat Achilles tendon was cut and sutured by a modified Kessler's technique with or without the collagen membrane wrapped.Macroscopic,morphological and biomechanical evaluations were applied to examine the recovery of the injured tendon at 4 and 8 weeks after surgery.Results The surgery group wrapped by collagen membranes had a better outcome than the group with surgery repair only.In the collagen membrane-treated group,less adhesion appeared,stronger tensile strength was detected,and more tendon fibers and collagen I expression were observed morphologically.Conclusion Wrapping the tendon with a collagen membrane may be an efficient approach for tendon repair and preventing tendon adhesion after its ruptures.